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Understanding the interactions between your analyte and the column stationary phase is invaluable at all stages of GC method development as this interaction is what governs the degree of retention and separation of that analyte.

These analyte/stationary phase interactions can be divided into three broad categories:

Dispersive, dipole, and hydrogen bonding interactions

In this video we will take a more in depth look at these important interactions.

GC Columns - Analyte/Stationary Phase Interactions