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Atmospheric pressure photoionization (APPI) is a complement to ESI and APCI and has been developed to broaden the range of ionizable analytes at atmospheric pressure. APPI is especially suited for low-polarity and non-polar compounds. In this module discover how to optimize experimental parameters when using APPI.

 

Topics include:

  • Ion sampling and transfer in APPI interfaces
  • Ionization mechanism
  • Analyte declustering strategies
  • Source parameter optimization
Atmospheric Pressure Photoionization (APPI) Technique